METABOLISM OF 14C-GLUFOSINATE AND 14C-N-ACETYL-GLUFOSINATE IN LACTATING GOATS AND LAYING HENS.= Omschrijving ==
Glufosinate ammonium (ammonium homoalanin-4-yl(methyl)phosphinate) and N-acetyl-glufosinate (the major metabolite in glufosinate resistant crops) were administered orally to lactating goats and laying hens. Goats were dosed with either glufosinate ammonium or N-acetyl-glufosinate for four and three days, respectively at approximately 92 ppm in the diet representing 60-75 times the maximum residue level expected in ruminant feed. Hens were dosed for fourteen days with either glufosinate ammonium or N-acetyl-glufosinate at approximately 26 ppm, representing 10 times the maximum residue level in poultry feed. Total radioactive residue levels were determined for tissues, eggs and milk (as appropriate). Glufosinate and N-acetyl-glufosinate were rapidly eliminated from ruminants and poultry, with a similar metabolic profile being found for each compound in both species. Glufosinate was metabolized to MP-propionic acid (3-methylphosphinicopropionic acid) with a minor amount of N-acetyl-glufosinate and MP-acetic acid. (2-methylphosphinico-acetic acid) N-acetyl-glufosinate was readily de-acetylated to glufosinate with further metabolism to MP-propionic acid and MP-acetic acid.
== Auteur(s) ==
* M N Huang. J.K. Rupprecht*, K.A. Stumpf*, and S.M. Smith, AgrEvo USA, Co., 703 NOR-AM Road, Pikeville, NC 27863, *Hoechst Schering AgrEvo GmbH, Frankfurt, Germany (1995)
== Externe Links ==
Archief TSS: Bezwaarschriften en commentaren van Lily Eijsten.