University of Newcastle Research on the Transfer of DNA from GM Food into Bacteria in the Human Gut

To see if horizontal gene transfer was occurring, they tested the bacteria in the stools of the seven using colostomy bags before and six hours after the GM meal for the presence of the transgene. The wet bowel samples contained c.1 million bacteria per gram.
They could not detect any transgenes in the gut bacteria using normal PCR methods. However, after multiplying the bacteria in a broth to make detection more sensitive, they found that, in three of the seven volunteers, they had taken up a fragment of the transgenic epsps gene (conventional culture techniques cannot recover more than a tiny minority of the microbes in the gastrointestinal tract).
Lees verder “University of Newcastle Research on the Transfer of DNA from GM Food into Bacteria in the Human Gut”

Vergunning Avebe met genetisch gemanipuleerde aardappel nietig verklaard

De Raad van State heeft een vergunning nietig verklaard die door het ministerie van VROM aan aardappelzetmeelproducent Avebe verleend was voor een proef met genetisch gemodificeerde aardappelplanten waarin het kgz-gen is gebracht.
De proef zou op percelen in de gemeenten Aa en Hunze, Borger-Odoorn, Eemsmond, Emmen, Pekela en Veendam uitgevoerd hebben moeten worden.

De Raad is van oordeel dat het besluit niet voldoet aan de eis van een kenbare motivering. Greenpeace had de zaak aangespannen.

Bron: Raad van State, uitspraak 20-04-2005:  vernietiging besluit DGM/SAS nr. BGGO 03/04

A profile of Monsanto in South Africa

An information document produced by African Centre for Biosafety

Monsanto has been active in the agrochemicals market in South Africa since 1968, with 19 registered herbicides. Glyphosate, the active ingredient of Roundup, has been offpatent in South Africa since 1990 and Monsanto has faced competition from a number of other producers of the chemical since then. Monsanto has maintained market dominance by obliging farmers using its Roundup Ready GM crops to use only Monsanto’s herbicides on the crops.

Bron:  African Centre for Biosafety, april 2005:  A PROFILE OF MONSANTO IN SOUTH AFRICA

EU weert Amerikaanse genmaïs

De Europese Unie gooit per direct de grenzen dicht voor alle genmaïs uit Amerika. De EU vreest dat het maïs is vermengd met het verboden maïstype BT-10.
De EU-landen hebben dat vrijdag in Brussel bijna unaniem besloten, meldde Europees Commissaris Kyprianou (Volksgezondheid).
Nederland was voor de noodmaatregel.

BT-10 bevat een gen dat een bepaald antibioticum (een ampicillineresistentiegen) uitschakelt.

Bron: Volkskrant, 15-04-2005:  EU gooit grens dicht voor Amerikaans genmaïs

Stop het genetisch manipuleren van pokken

Ga daarvoor naar www.smallpoxbiosafety.org om een (voorgedrukte) brief te struren naar de WHO.

URGENT ALERT! TAKE ACTION NOW!

STOP SMALLPOX GENETIC ENGINEERING!

Please take action now to stop smallpox genetic engineering!  Visit www.smallpoxbiosafety.org to send a letter to the WHO
Director General, urging the World Health Assembly to reject a proposal that would permit the genetic engineering of
smallpox, and to instead ensure that all remaining stocks of the virus are destroyed within two years.

The proposal to genetically engineer smallpox, which would also permit smallpox genes to be inserted into related
poxviruses and the unlimited distribution of small segments of smallpox DNA, poses a large number of public health,
biosafety, and biological weapons risks.

The World Health Assembly will discuss the proposal when it
meets in Geneva, Switzerland from 16-25 May 2005.

Bron: www.smallpoxbiosafety.org, 4-4-2005

Controversy over Gene Therapy ‘Breakthrough’

A ‘precision’ gene therapy turns out to have significant off-target effects
Dr. Mae-Wan Ho, Isis Press Release

Collateral damage from ‘precision’ gene therapy

A gene therapy technique, hailed as 2002’s ‘breakthrough of the year’ in its ability to shut down specifically and precisely any chosen gene, has been found not to be so specific or precise after all. The technique involves RNA interference (“Subverting the genetic text”, SiS 24 ), the ability of a short specific duplex sequence of RNA to target the transcript of gene, thereby shutting it down. Unfortunately, there are “off-target” effects on other genes and proteins.

The technique depends on a perfect match between the siNA (small interfering RNA) introduced and its complementary sequence in the gene transcript. Only sequences of 19-21 base pairs are generally used, as longer sequences induce nonspecific immune reactions.

However, various mismatches between the siRNA and its target appear to be tolerated, so that other transcripts with similar sequences are also affected.

Bron: I-SIS. 5-4-2005: Controversy over Gene Therapy ‘Breakthrough’