2-22-2020 GMWatch: “Adding to the list of problems that can occur with CRISPR, a new study shows that when the CRISPR/Cas system was used in a gene editing procedure aimed at inserting genetic material in mice, a high frequency was found of insertions of multiple copies of the DNA molecules used as…” More
Paper: Pervasive head-to-tail insertions of DNA templates mask desired CRISPR-Cas9–mediated genome editing events.
See all authors and affiliations Science Advances 12 Feb 2020:
Vol. 6, no. 7, eaax2941
DOI: 10.1126/sciadv.aax2941